
Exploring Real-Time Monitoring for Complex Cell Systems
Achieve seamless, continuous insights into luminescent cell systems without disruption.
Partnering with researchers to develop solutions for continuous, non-invasive monitoring of luminescent reporter cells in advanced in vitro systems like organ-on-a-chip (OOAC) and microphysiological models.
Join us in shaping the future of cell system monitoring. Share your insights or register your interest to collaborate at lumicell.com
Current Challenges
The latest generation of in-vitro cell model systems do little to incorporate continuous measurement of important biological outputs such as gene expression. Often, the only way to measure changes over time is destructive harvesting at multiple timepoints for endpoint measures such as PCR or immunostaining, resulting in unnecessary replication of experiments, incurring considerable additional costs in consumables and skilled researcher time.
We believe that researchers want better real-time monitoring that can be used with their established in vitro models. Current monitoring solutions either require cell samples to be moved to a plate reader or microscope, disrupting the experiment, or do not interface with OOAC and other complex cell systems.

Value Proposition
The LumoCell Solution
We’re developing innovative approaches that use luminescent reporter cells to provide real-time insights into gene expression. Our vision is to create a system combining sensitive detection hardware with automated data processing to allow continuous monitoring, reduce disruptions, and improve efficiency.
We’re seeking feedback and collaboration from researchers to refine and tailor this technology for real-world needs.
Proposed Features We Are Exploring
Real-Time Monitoring
Real-time, non-invasive monitoring of biological outputs.
Luminescent Detection
Luminescent detection to track gene expression dynamically.
Remote Alerts
Automated data processing for seamless insights.
Compatibility
Compatibility with advanced systems like OOAC and microphysiological models.
LumoCell Approach
We plan to use luciferases, enzymes that produce light, to make cells which can indicate the level of expression of genes of interest. We will provide sensitive detection hardware to monitor the small amount of light emitted by these cells.
Our logging software automatically collects, processes and presents data, remotely sending alerts or updates if required.
As a result, our users are able to monitor biological outcomes continuously and perform time course experiments with fewer materials and with less human input.

Market Exploration
We are keen to engage with:
- Pharma Teams: Collaborate with us to explore how real-time monitoring can enhance drug discovery processes
- Biotech Firms: Help shape the next generation of tools for cell model innovation
- Academics: Partner with us to refine and adapt this technology for cutting-edge research
FAQs
How does LumoCell work?
We’re exploring the use of luminescent reporter cells combined with sensitive detection hardware to provide continuous monitoring of gene expression in real-time.
Is this technology ready to use?
Not yet. We’re in the prototyping stage and are actively seeking input from researchers to refine and adapt the technology to meet your needs.
Can I request a demo?
While we’re not offering demos at this stage, we’d love to discuss your challenges and gather insights to shape the final product.

LumoCell
Register your interest
Join us in developing the future of in vitro monitoring. Register your interest or share your insights at lumocell.com.